National Oral Disability Centre, Institute for Postgraduate Dental Education, Jönköping, Sweden.
Acta Odontol Scand. 2009;67(6):377-81. doi: 10.1080/00016350903160571.
To screen orofacial function in people with various ectodermal dysplasia (ED) syndromes and compare with a healthy reference sample.
The ED group comprised 46 individuals (30 M and 16 F; mean age 14.5 years, range 3-55). Thirty-two had hypohidrotic ED, while 14 had other ED syndromes. The reference sample comprised 52 healthy individuals (22 M and 30 F; mean age 24.9 years, range 3-55). Orofacial function was screened using the Nordic Orofacial Test-Screening (NOT-S) protocol containing 12 orofacial function domains (maximum score 12 points).
The total NOT-S score was higher in the ED group than in the healthy group (mean 3.5 vs. 0.4; p<0.001). The dysfunctions most frequently recorded in the subjects with ED occurred in the domains chewing and swallowing (82.6%), dryness of the mouth (45.7%), and speech (43.5%). Those with other ED syndromes scored non-significantly higher than those with hypohidrotic ED (mean 4.6 vs. 3.0; p>0.05).
Individuals with ED scored higher than a healthy reference sample in all NOT-S domains, especially in the chewing and swallowing, dryness of the mouth, and speech domains. Orofacial function areas and treatment and training outcomes need to be more closely evaluated and monitored.
筛选不同外胚层发育不良（ED）综合征患者的口腔颌面部功能，并与健康参考样本进行比较。
ED 组包括 46 名个体（30 名男性和 16 名女性；平均年龄 14.5 岁，范围 3-55 岁）。32 名患者患有少汗型 ED，14 名患者患有其他 ED 综合征。参考样本包括 52 名健康个体（22 名男性和 30 名女性；平均年龄 24.9 岁，范围 3-55 岁）。使用包含 12 个口腔颌面部功能域（最高得分为 12 分）的北欧口腔面部测试-筛选（NOT-S）方案筛选口腔颌面部功能。
ED 组的 NOT-S 总分高于健康组（平均 3.5 分比 0.4 分；p<0.001）。ED 患者最常记录的功能障碍发生在咀嚼和吞咽（82.6%）、口干（45.7%）和言语（43.5%）领域。其他 ED 综合征患者的评分明显高于少汗型 ED 患者（平均 4.6 分比 3.0 分；p>0.05）。
ED 患者在所有 NOT-S 域的评分均高于健康参考样本，尤其是在咀嚼和吞咽、口干和言语领域。需要更密切地评估和监测口腔颌面部功能区域以及治疗和训练结果。
