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白血病患者在拔除创伤性 Hickman 导管后发生播散性原绿球藻病。

Disseminated protothecosis following traumatic Hickman line removal in a patient with leukaemia.

机构信息

Microbiology, Royal Gwent Hospital, Newport, Wales NP202UB, UK.

出版信息

Med Mycol. 2010 Mar;48(2):410-2. doi: 10.1080/13693780903188698.

Abstract

Human protothecosis is a rare infection caused by a member of the genus Prototheca, an ubiquitous alga. Traumatic inoculation can cause infections in the immunocompetent host while disseminated infection is mainly seen in patients with compromised immunity. We report here an unusual case of disseminated infection in a cancer patient. Traumatic removal of a Hickman catheter in this patient, led to the development of a severe skin and subcutaneous tissue infection with algaemia. These infections are often indolent and difficult to treat, with paucity of information available as to guidelines for diagnosis and effective therapeutic options.

摘要

人体原绿球藻病是一种由原绿球藻属成员引起的罕见感染,原绿球藻属是一种无处不在的藻类。创伤性接种会导致免疫功能正常的宿主发生感染,而播散性感染主要见于免疫功能受损的患者。我们在此报告一例癌症患者的散发性感染的不寻常病例。该患者在创伤性移除 Hickman 导管后,发生了严重的皮肤和皮下组织感染伴藻类血症。这些感染通常较为隐匿且难以治疗,有关诊断和有效治疗选择的指南信息也很有限。

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