Sucher Robert, Hautz T, Brandacher G, Lee W P Andrew, Margreiter R, Schneeberger S
Medizinische Universität Insbruck, Abteilung für Allgemein-, Transplantations- und Thoraxchirurgie, Innsbruck, Austria.
Handchir Mikrochir Plast Chir. 2009 Aug;41(4):217-23. doi: 10.1055/s-0029-1234062. Epub 2009 Aug 17.
Avoidance or minimization of maintenance immunosuppression represents the key step for promoting wider applicability of reconstructive transplantation. Understanding the mechanisms of composite tissue allograft rejection is of essence in working towards this goal. We herein review the current knowledge on acute rejection in reconstructive transplantation and discuss findings in the light of novel immunosuppressive and immunomodulatory strategies.
