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铁蛋白-凝集素缀合物与完整细胞中C型病毒的结合。

Binding of ferritin-lectin conjugates to C-type virus in intact cells.

作者信息

Manuelidis L, Tomita M, Manuelidis E E

出版信息

Experientia. 1977 Jul 15;33(7):949-52. doi: 10.1007/BF01951299.

Abstract

Ferritin-Ricin II and Ferritin-Concanavalin A bound to budding as well as mature C-type viral particles. No differencies in binding between the viral coat and adjacent plasma membrane were detected with either lectin conjugate. Aggregation of viral particles by lectin conjugates was observed, and linking of virus to the plasma membrane resulted in phagocytosis of viral particles.

摘要

铁蛋白-蓖麻毒素II和铁蛋白-伴刀豆球蛋白A与出芽的以及成熟的C型病毒颗粒结合。用这两种凝集素缀合物均未检测到病毒衣壳与相邻质膜之间在结合上存在差异。观察到凝集素缀合物使病毒颗粒聚集,并且病毒与质膜的连接导致病毒颗粒被吞噬。

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