Woo Victoria, Bonks Julia, Borukhova Lyubov, Zegarelli David
School of Dental Medicine, University of Nevada, Las Vegas, Nevada, USA.
Pediatr Dermatol. 2009 Jul-Aug;26(4):458-64. doi: 10.1111/j.1525-1470.2009.00953.x.
Lichenoid drug eruptions are seen most frequently on the skin and seldomly affect the mucosal surfaces. Oral involvement-known as oral lichenoid drug eruption-is more common in the adult population and has been associated with numerous medications. Pediatric-onset oral lichenoid drug eruption is an exceptionally rare finding with only isolated cases published in the literature. The nonspecific appearance and latent presentation of pediatric oral lichenoid drug eruption can cause confusion in diagnosis and treatment. We report a case of oral lichenoid drug eruption occurring in a 15-year-old and explore challenges in the clinical and histologic recognition of this condition.
苔藓样药疹最常出现在皮肤上，很少累及黏膜表面。口腔受累——称为口腔苔藓样药疹——在成人中更为常见，且与多种药物有关。儿童期发病的口腔苔藓样药疹极为罕见，文献中仅报道过个别病例。儿童口腔苔藓样药疹的非特异性表现和隐匿性发作会导致诊断和治疗上的困惑。我们报告一例15岁患者发生的口腔苔藓样药疹，并探讨这种疾病在临床和组织学识别方面的挑战。
