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胃癌(生物标志物)知识库(GCBKB):一个经过整理且完全整合的与胃癌相关的假定生物标志物知识库。

Gastric Cancer (Biomarkers) Knowledgebase (GCBKB): A Curated and Fully Integrated Knowledgebase of Putative Biomarkers Related to Gastric Cancer.

作者信息

Lee Bernett T K, Song Chun Meng, Yeo Boon Huat, Chung Cheuk Wang, Chan Ying Leong, Lim Teng Ting, Chua Yen Bing, Loh Marie C S, Ang Boon Keong, Vijayakumar Praveen, Liew Lailing, Lim Jiahao, Lim Yun Ping, Wong Chee Hong, Chuon Danny, Rajagopal Gunaretnam, Hill Jeffrey

机构信息

Bioinformatics Institute, 30 Biopolis Street, #07-01 Matrix, Singapore 138671, Singapore.

出版信息

Biomark Insights. 2007 Feb 7;1:135-41.

PMID:19690644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2716787/
Abstract

The Gastric Cancer (Biomarkers) Knowledgebase (GCBKB) (http://biomarkers.bii.a-star.edu.sg/background/gastricCancerBiomarkersKb.php) is a curated and fully integrated knowledgebase that provides data relating to putative biomarkers that may be used in the diagnosis and prognosis of gastric cancer. It is freely available to all users. The data contained in the knowledgebase was derived from a large literature source and the putative biomarkers therein have been annotated with data from the public domain. The knowledgebase is maintained by a curation team who update the data from a defined source. As well as mining data from the literature, the knowledgebase will also be populated with unpublished experimental data from investigators working in the gastric cancer biomarker discovery field. Users can perform searches to identify potential markers defined by experiment type, tissue type and disease state. Search results may be saved, manipulated and retrieved at a later date. As far as the authors are aware this is the first open access database dedicated to the discovery and investigation of gastric cancer biomarkers.

摘要

胃癌(生物标志物)知识库(GCBKB)(http://biomarkers.bii.a-star.edu.sg/background/gastricCancerBiomarkersKb.php)是一个经过精心策划且完全整合的知识库,提供与可能用于胃癌诊断和预后的假定生物标志物相关的数据。所有用户均可免费使用。知识库中的数据源自大量文献来源,其中的假定生物标志物已用来自公共领域的数据进行注释。该知识库由一个编辑团队维护,他们从指定来源更新数据。除了从文献中挖掘数据外,知识库还将收录来自从事胃癌生物标志物发现领域的研究人员的未发表实验数据。用户可以进行搜索,以识别按实验类型、组织类型和疾病状态定义的潜在标志物。搜索结果可以保存、处理并在以后检索。据作者所知,这是第一个致力于胃癌生物标志物发现和研究的开放获取数据库。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c6/2716787/8300d549a436/bmi-2006-135f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c6/2716787/0dd3372bd55d/bmi-2006-135f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c6/2716787/8300d549a436/bmi-2006-135f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c6/2716787/0dd3372bd55d/bmi-2006-135f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8c6/2716787/8300d549a436/bmi-2006-135f2.jpg

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本文引用的文献

1
Diagnostics and biomarker development: priming the pipeline.
Nat Rev Drug Discov. 2006 Jun;5(6):463-9. doi: 10.1038/nrd2033. Epub 2006 May 19.
2
Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer.检测胃灌洗液中的端粒酶活性:一种检测胃癌的新方法。
J Surg Res. 2006 Apr;131(2):252-5. doi: 10.1016/j.jss.2005.11.567. Epub 2006 Jan 19.
3
Pfam: clans, web tools and services.蛋白质家族数据库(Pfam):家族分类、网络工具及服务
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D247-51. doi: 10.1093/nar/gkj149.
CBD:结直肠癌的生物标志物数据库。
Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay046.
4
IDBD: infectious disease biomarker database.IDBD:传染病生物标志物数据库。
Nucleic Acids Res. 2008 Jan;36(Database issue):D455-60. doi: 10.1093/nar/gkm925. Epub 2007 Nov 3.
4
Risk factors associated with the development of intestinal metaplasia in first-degree relatives of gastric cancer patients.胃癌患者一级亲属中与肠化生发生相关的危险因素。
Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2982-6. doi: 10.1158/1055-9965.EPI-05-0181.
5
Fruits, vegetables, and antioxidants and risk of gastric cancer among male smokers.水果、蔬菜、抗氧化剂与男性吸烟者患胃癌的风险
Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2087-92. doi: 10.1158/1055-9965.EPI-05-0038.
6
Recent advances in biomarkers for cancer diagnosis and treatment.癌症诊断与治疗生物标志物的最新进展。
Drug Discov Today. 2005 Jul 15;10(14):965-76. doi: 10.1016/S1359-6446(05)03487-2.
7
Polymorphism and gastric cancer.
J Gastroenterol Hepatol. 2005 May;20(5):793-4. doi: 10.1111/j.1440-1746.2005.03938.x.
8
The Biomolecular Interaction Network Database and related tools 2005 update.生物分子相互作用网络数据库及相关工具2005年更新版
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D418-24. doi: 10.1093/nar/gki051.
9
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Nucleic Acids Res. 2005 Jan 1;33(Database issue):D154-9. doi: 10.1093/nar/gki070.
10
Persistent infection with Helicobacter pylori and the development of gastric cancer.幽门螺杆菌持续感染与胃癌的发生
Adv Cancer Res. 2003;90:63-89. doi: 10.1016/s0065-230x(03)90002-9.