Plastic Surgery Clinic, Numune Training and Research Hospital, Ankara, Turkey.
Aesthetic Plast Surg. 2009 Sep;33(5):730-7. doi: 10.1007/s00266-009-9396-y. Epub 2009 Aug 19.
Clinical studies have revealed that liposuction causes systemic fat mobilization. However, the degree of the risk it causes is not clear. In this study we investigated the risk of systemic fat mobilization and fat embolus in rats following liposuction using dry and tumescent techniques.
At the end of the procedures, the rats were sacrificed and specimens were obtained from the lungs, kidneys, liver, brain, and skin. Histological examinations of the specimens were carried out. Liposuction was not performed in the control group (n = 8), but blood and tissue specimens for histological examinations were obtained.
We found signs of fat embolus in both blood specimens and histological examinations of tissue samples in the study groups. However, the results of the examinations were normal in the control group. Although there were no fat particles in the blood before liposuction, blood specimens obtained following the procedures and in the long-term had fat particles.
临床研究表明，抽脂会引起全身脂肪动员。然而，其引起的风险程度尚不清楚。在这项研究中，我们使用干式和肿胀技术研究了抽脂后大鼠全身脂肪动员和脂肪栓子的风险。
手术结束时，处死大鼠并从肺、肾、肝、脑和皮肤中获取标本。对标本进行组织学检查。对照组（n = 8）未进行抽脂，但为组织学检查获取了血液和组织标本。
我们在研究组的血液标本和组织样本的组织学检查中均发现了脂肪栓子的迹象。然而，对照组的检查结果正常。虽然抽脂前血液中没有脂肪颗粒，但手术后和长期随访时的血液标本中都有脂肪颗粒。
