Wang Hui-Dong, Zheng Jiang-Hong, Deng Chen-Liang, Liu Qin-Yang, Yang Song-Lin
Shanghai No 6 People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Aesthetic Plast Surg. 2008 Sep;32(5):731-6. doi: 10.1007/s00266-008-9183-1. Epub 2008 May 29.
Fat embolism syndrome (FES) after liposuction is likely a life-threatening disorder, though its incidence is low. The three chief clinical manifestations include respiratory insufficiency, cerebral involvement, and petechial rash. Although FES is a multisystem disorder, the most seriously affected organs are the lungs, brain, cardiavascular system, and skin. Many laboratory findings are characteristic but nonspecific. The pathogenesis of FES after liposuction has been looked at both mechanically and biochemically. Diagnosis is difficult; Gurd and Wilson's diagnostic criteria based on clinical examination is still extensively used in clinics at present. There is no specific therapy for FES after liposuction for the moment, so prevention, early diagnosis, and supportive therapies are important. In this article we discuss the clinical presentation, pathogensis, and current methods to prevent FES and, if possible, ways to treat this complication.
抽脂术后脂肪栓塞综合征（FES）虽发病率低，但可能是一种危及生命的疾病。其三大主要临床表现包括呼吸功能不全、脑部受累及瘀点疹。尽管FES是一种多系统疾病，但受影响最严重的器官是肺、脑、心血管系统和皮肤。许多实验室检查结果具有特征性但不具特异性。抽脂术后FES的发病机制已从机械和生化两方面进行研究。诊断困难；目前临床上仍广泛使用基于临床检查的Gurd和Wilson诊断标准。目前抽脂术后FES尚无特异性治疗方法，因此预防、早期诊断和支持性治疗很重要。在本文中，我们讨论了其临床表现、发病机制、目前预防FES的方法以及可能的话治疗这种并发症的方法。
