Penn Heidi A, DeMarco Romano T, Sherman Ashley K, Gatti John M, Murphy J Patrick
Division of Pediatric Urology and Medical Research-Biostatistics, Children's Mercy Hospital, Kansas City, Missouri 64108, USA.
J Urol. 2009 Oct;182(4 Suppl):1824-7. doi: 10.1016/j.juro.2009.03.018. Epub 2009 Aug 18.
To gain better understanding of ESWL efficacy in children with renal calculi we report our outcomes using this technique.
We reviewed the records of children who underwent ESWL as monotherapy for renal calculi at our institution from 1988 to 2007. Data included clinical characteristics, stone-free rate and its relationship to stone size and location, lithotriptor and complications.
The 33 boys and 29 girls with an average age of 10 years underwent a total of 69 treatments. A 53% and 63% stone-free rate was achieved after 1 and 2 ESWL sessions, respectively. A trend toward a higher stone-free rate (61% to 70%) after 1 ESWL session was seen in children with stones less than 50 mm(2), renal pelvic stones and treatment with the Dornier HM3 lithotriptor. Children with stones greater than 100 mm(2), a caliceal location and those treated with the Dornier MFL 5000 lithotriptor had a higher failure rate (25% to 46%). Five patients (8%) required ureteroscopy after ESWL due to retained distal ureteral stone fragments. Five patients (8%) who were not stone-free after therapy required subsequent endoscopic treatment for the stone during followup.
Smaller renal stones, renal pelvic calculi and treatment with an older generation lithotriptor were independent variables associated with a higher stone-free rate in children. While ESWL is a simple method in children with renal calculi, those with large or caliceal stones may do best with a primary endoscopic approach.
为了更好地了解体外冲击波碎石术(ESWL)治疗儿童肾结石的疗效,我们报告了使用该技术的治疗结果。
我们回顾了1988年至2007年在我院接受ESWL单一疗法治疗肾结石的儿童记录。数据包括临床特征、无结石率及其与结石大小和位置的关系、碎石机及并发症。
33名男孩和29名女孩,平均年龄10岁,共接受了69次治疗。分别在1次和2次ESWL治疗后,无结石率达到53%和63%。结石小于50mm²、肾盂结石且使用多尼尔HM3碎石机治疗的儿童,在1次ESWL治疗后无结石率有升高趋势(61%至70%)。结石大于100mm²、位于肾盏且使用多尼尔MFL 5000碎石机治疗的儿童,失败率较高(25%至46%)。5名患者(8%)在ESWL治疗后因输尿管远端残留结石碎片需要输尿管镜检查。5名治疗后未达到无结石状态的患者在随访期间需要后续的内镜下结石治疗。
较小的肾结石、肾盂结石以及使用较老式碎石机治疗是与儿童较高无结石率相关的独立变量。虽然ESWL对儿童肾结石是一种简单的治疗方法,但对于结石较大或位于肾盏的患儿,采用初次内镜治疗方法可能效果最佳。