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女性尿道上裂的治疗:会阴尿道宫颈成形术与经典的扬-迪斯手术对比

Female epispadias management: perineal urethrocervicoplasty versus classical Young-Dees procedure.

作者信息

Cheikhelard Alaa, Aigrain Yves, Lottmann Henri, Lortat-Jacob Stephen

机构信息

Department of Pediatric Surgery and Urology, Assistance Publique-Hôpitaux de Paris Hôpital Necker Enfants-Malades, Paris, France.

出版信息

J Urol. 2009 Oct;182(4 Suppl):1807-11. doi: 10.1016/j.juro.2009.04.087. Epub 2009 Aug 18.

Abstract

PURPOSE

We compared the functional results of 1-stage perineal urethrocervicoplasty and vulvoplasty vs the classic Young-Dees procedure for incontinent female epispadias.

MATERIALS AND METHODS

We treated 14 female patients with incontinent epispadias between 1997 and 2007, of whom 7 each underwent the Young-Dees procedure until 2004 (group 1) and 1-stage urethrocervicoplasty with vulvoplasty through a perineal subsymphyseal approach (group 2). We retrospectively compared patient age at surgery, bladder capacity, continence outcome and postoperative morbidity.

RESULTS

The groups were comparable except for age at procedure. In group 1 vs 2 surgery was performed at a median age of 6 vs 4 years. In groups 1 and 2 median preoperative bladder capacity was 120 and 100 cc, and mean followup was 8 and 2.5 years, respectively. Six group 1 patients achieved continence, including 5 with overnight continence, but 5 required additional surgery to enhance continence or voiding, including pericervical injections of bulking agents (3), cervicotomy or urethral calibration (4) and enterocystoplasty (1). Two patients required long-term clean intermittent catheterization, 4 underwent upper tract dilation postoperatively and 4 had a total of 8 episodes of febrile urinary tract infection. Six group 2 patients were continent, including 3 with overnight continence (p = 1). None required clean intermittent catheterization even temporarily or any additional surgery (p = 0.02). Only 2 patients had a febrile urinary tract infection (p = 0.25).

CONCLUSIONS

Reconstructing the bladder neck and urethra via a perineal approach for female epispadias is promising. Surgery may be performed earlier with similar continence results, less postoperative morbidity and less need for additional surgery. Long-term studies are needed to confirm these preliminary results.

摘要

目的

我们比较了一期会阴尿道宫颈成形术和外阴成形术与经典的Young-Dees手术治疗女性尿失禁型膀胱外翻的功能结果。

材料与方法

1997年至2007年间,我们治疗了14例女性尿失禁型膀胱外翻患者,其中7例在2004年前接受了Young-Dees手术(第1组),另外7例通过会阴耻骨联合下途径接受了一期尿道宫颈成形术和外阴成形术(第2组)。我们回顾性比较了手术时患者年龄、膀胱容量、控尿结果和术后发病率。

结果

除手术时年龄外,两组具有可比性。第1组与第2组手术时的中位年龄分别为6岁和4岁。第1组和第2组术前中位膀胱容量分别为120 cc和100 cc,平均随访时间分别为8年和2.5年。第1组6例患者实现控尿,其中5例夜间控尿,但5例需要额外手术以改善控尿或排尿,包括宫颈周围注射填充剂(3例)、宫颈切开术或尿道扩张术(4例)以及肠膀胱扩大术(1例)。2例患者需要长期清洁间歇性导尿,4例术后接受上尿路扩张,4例共发生8次发热性尿路感染。第2组6例患者实现控尿,其中3例夜间控尿(p = 1)。无一例需要临时或任何额外手术(p = 0.02)。仅2例患者发生发热性尿路感染(p = 0.25)。

结论

通过会阴途径重建女性膀胱外翻患者的膀胱颈和尿道前景良好。手术可在更早年龄进行,控尿结果相似,术后发病率更低,且更少需要额外手术。需要长期研究来证实这些初步结果。

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