Terracol R, Iturbide Y, Prud'Homme N
Centre de Génétique Moléculaire, CNRS, Gif-sur-Yvette, France.
Biol Cell. 1990;68(1):65-71. doi: 10.1111/j.1768-322x.1990.tb00895.x.
In Drosophila melanogaster the tandemly arranged repetitive sequences coding for 18S and 28S rRNA are heterogenous at the level of the spacers between units and insertions that interrupt many 28S rRNA genes. This heterogeneity contrasts with the homogeneity of the regions transcribed into 18S and 28S rRNA. Homogenization and evolution of repetitive genes are usually explained by conversion, amplification events or unequal crossovers. In this paper we studied the change in rDNA patterns associated with partial reversion of bobbed mutations. In most cases, no increase in rDNA gene number, but a new repartition of gene types were found.
在黑腹果蝇中,编码18S和28S核糖体RNA的串联排列重复序列在单位间隔区和中断许多28S核糖体RNA基因的插入序列水平上是异质的。这种异质性与转录为18S和28S核糖体RNA的区域的同质性形成对比。重复基因的同质化和进化通常通过转换、扩增事件或不等交换来解释。在本文中,我们研究了与截毛突变部分回复相关的核糖体DNA模式的变化。在大多数情况下,未发现核糖体DNA基因数量增加,但发现了基因类型的新分布。