Bayés Alex, Grant Seth G N
Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK.
Nat Rev Neurosci. 2009 Sep;10(9):635-46. doi: 10.1038/nrn2701.
Advances in technology have equipped the field of neuroproteomics with refined tools for the study of the expression, interaction and function of proteins in the nervous system. In combination with bioinformatics, neuroproteomics can address the organization of dynamic, functional protein networks and macromolecular structures that underlie physiological, anatomical and behavioural processes. Furthermore, neuroproteomics is contributing to the elucidation of disease mechanisms and is a powerful tool for the identification of biomarkers.
技术进步为神经蛋白质组学领域配备了精密工具，用于研究神经系统中蛋白质的表达、相互作用和功能。结合生物信息学，神经蛋白质组学能够研究构成生理、解剖和行为过程基础的动态功能蛋白质网络和大分子结构的组织情况。此外，神经蛋白质组学有助于阐明疾病机制，是识别生物标志物的有力工具。
