Post Graduate Institute of Medical Eduction and Research, Chandigarh, India.
Rheumatol Int. 2010 Sep;30(11):1503-5. doi: 10.1007/s00296-009-1098-x. Epub 2009 Aug 21.
Intravenous immunoglobulin (IVIg) is emerging as the mainstay in the treatment of many autoimmune diseases, including systemic lupus erythematosus. IVIg has been found to be beneficial in myocarditis due to dermatomyositis/polymyositis, Kawasaki disease, and viral myocarditis in children. We report an 18-year-old man of active lupus with worsening cardiac systolic function who did not respond to pulse methylprednisolone and cyclophosphamide, but subsequently showed an improvement in his cardiac function after IVIg administration.
静脉注射免疫球蛋白 (IVIg) 作为治疗多种自身免疫性疾病的主要方法正在兴起,包括系统性红斑狼疮。IVIg 已被发现对皮肌炎/多发性肌炎、川崎病和儿童病毒性心肌炎引起的心肌炎有益。我们报告了一例活动性狼疮患者,该患者心脏收缩功能恶化,对脉冲甲基强的松龙和环磷酰胺治疗无反应,但随后在接受 IVIg 治疗后心脏功能得到改善。