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青少年进行性结缔组织病相关心肌炎致死

Fatal Myocarditis in an Adolescent Girl with Evolving Connective Tissue Disease.

机构信息

Department of Pediatrics, Rajagiri Hospital, Aluva, Kerala, 683112, India.

Department of Clinical Immunology and Rheumatology, Rajagiri Hospital, Aluva, Kerala, India.

出版信息

Indian J Pediatr. 2019 Sep;86(9):857-859. doi: 10.1007/s12098-019-02974-9. Epub 2019 May 10.

Abstract

Connective tissue diseases are rarely suspected and diagnosed in childhood and adolescence. Rarity of occurrence and poor disease acceptance among parents make them extremely difficult to treat in the early stages. An adolescent girl presented with features of pneumonia, was worked up and diagnosed as an evolving connective tissue disease. Her clinical characteristics did not fit into any specific disease. She was started on steroids and immunoglobulin as she had fulminant myocarditis with rapid downhill clinical course. High index of suspicion and aggressive immunosuppression can be life saving in exceptional situations even though a specific diagnosis cannot be ascertained.

摘要

结缔组织病在儿童和青少年中很少被怀疑和诊断。由于发病罕见,且父母对疾病的认识不足,使得这些疾病在早期极难治疗。一名少女表现出肺炎的特征,经过检查被诊断为一种进行性结缔组织病。她的临床特征不符合任何特定的疾病。由于她患有暴发性心肌炎,病情迅速恶化,因此开始使用类固醇和免疫球蛋白进行治疗。在特殊情况下,即使无法确定明确的诊断,高度怀疑和积极的免疫抑制治疗也可以挽救生命。

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