Bie Li-Li, Ma Hong-Wei, Chen Zan, Zhang Bo-Wei
Institute of Transfusion Medicine, Henan Provincial Red Cross Blood Center, Zhengzhou 450012, Henan Province, China.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Aug;17(4):1071-3.
The study was aimed to analyze Del phenotype of RhD (-) unrelated blood donors. RhD (-) was initially screened by routine serological test and confirmed by indirect antiglobulin test (IAT). Del phenotype was detected by hot-ether absorption-elution test. The results indicated that 106 RhD (-) samples were confirmed out of 38526 donors, and 28 cases were Del detected by hot-ether absorption-elution test. The incidence of Del in RhD (-) samples was 26.41%, The serological phenotypes of Del were Ccee (78.57%), CCee (14.29%) and CcEe (7.14%) respectively. In conclusion, the detection of Del by using hot-ether absorption-elution test is very important for reasonable application of RhD (-) blood. There is difference in Del phenotypes of populations in different regions of China and Japan.
本研究旨在分析RhD（-）无偿献血者的Del血型表型。RhD（-）最初通过常规血清学检测进行筛查，并通过间接抗球蛋白试验（IAT）进行确认。Del血型表型通过热乙醚吸收-洗脱试验检测。结果表明，在38526名献血者中，共确认106例RhD（-）样本，其中通过热乙醚吸收-洗脱试验检测出28例Del。RhD（-）样本中Del的发生率为26.41%，Del的血清学表型分别为Ccee（78.57%）、CCee（14.29%）和CcEe（7.14%）。综上所述，采用热乙醚吸收-洗脱试验检测Del对于RhD（-）血液的合理应用非常重要。中国和日本不同地区人群的Del血型表型存在差异。
