Rofail Diana, Heelis Rebecca, Gournay Kevin
Questionnaire Development and Validation Unit, Mapi Values, Adelphi Mill, Bollington, Cheshire, United Kingdom. diana.rofailccswamscale.co.uk
Clin Ther. 2009 Jun;31 Pt 1:1488-96. doi: 10.1016/j.clinthera.2009.07.001.
Approximately 50% of patients with schizophrenia do not adhere to their antipsychotic medication regimens, partly because of their concerns about medication.
The aim of this study was to investigate the experiences of patients with schizophrenia during treatment with antipsychotic medication.
As part of the SWAM (Satisfaction With Antipsychotic Medication) Scale (registered to Diana Rofail, Cheshire, United Kingdom) validation study, a convenience sample of patients with schizophrenia responded to an open-ended question regarding their treatment experiences with antipsychotic medication. Thematic analysis was performed. Each item was studied repeatedly, and relevant extracts from the data set were collated to form themes. Themes were then checked against each other and against the original data set to ensure that they were coherent, consistent, and distinctive. The process was predominantly inductive and data driven.
A convenience sample of 80 participants (35 women and 45 men), aged 35 to 44 years, reported their treatment experiences with antipsychotic medication. Nine themes were identified: (1) symptoms of illness; (2) importance and helpfulness of medication; (3) adverse events and negative impact; (4) desire to stop medication; (5) knowledge and insight into the need for medication and its potential adverse effects; (6) feelings of being used as experimental subjects; (7) environment; (8) reservations about health care professionals; and (9) support from others.
These patients with schizophrenia reported a range of experiences during their treatment with antipsychotic medication.
约50%的精神分裂症患者不坚持其抗精神病药物治疗方案，部分原因是他们对药物存在担忧。
本研究旨在调查精神分裂症患者在抗精神病药物治疗期间的经历。
作为抗精神病药物满意度（SWAM）量表（已注册给英国柴郡的戴安娜·罗法伊尔）验证研究的一部分，一个精神分裂症患者的便利样本回答了一个关于他们抗精神病药物治疗经历的开放式问题。进行了主题分析。对每个项目进行反复研究，并整理数据集中的相关摘录以形成主题。然后将主题相互对照并与原始数据集对照，以确保它们连贯、一致且独特。该过程主要是归纳性的且由数据驱动。
一个由80名参与者（35名女性和45名男性）组成的便利样本，年龄在35至44岁之间，报告了他们的抗精神病药物治疗经历。确定了九个主题：（1）疾病症状；（2）药物的重要性和帮助；（3）不良事件和负面影响；（4）停药愿望；（5）对用药必要性及其潜在不良反应的认识和洞察；（6）被当作实验对象的感觉；（7）环境；（8）对医护人员的保留意见；（9）他人的支持。
这些精神分裂症患者报告了他们在抗精神病药物治疗期间的一系列经历。
