Cortés M J, Valero J, Gutiérrez-Zotes J A, Hernández A, Moreno L, Jariod M, Martorell L, Vilella E, Labad A
Unitat de Psiquiatria i Psicologia Mèdica, Department Medicina i Cirurgia, Fac. Medicina i Ciències de la Salut, Universitat Rovira i Virgili, C/ Sant Llorenç 21, 43201 Reus, Spain.
Eur Psychiatry. 2009 Oct;24(7):476-82. doi: 10.1016/j.eurpsy.2009.06.002. Epub 2009 Aug 20.
Personality dimensions have been associated with symptoms dimensions in schizophrenic patients (SP). In this paper we study the relationships between symptoms of functional psychoses and personality dimensions in SP and their first-degree relatives (SR), in other psychotic patients (PP) and their first-degree relatives (PR), and in healthy controls in order to evaluate the possible clinical dimensionality of these disorders. Twenty-nine SP, 29 SR, 18 PP, 18 PR and 188 controls were assessed using the temperament and character inventory (TCI-R). Current symptoms were evaluated with positive and negative syndrome scale (PANSS) using the five-factor model described previously (positive [PF], negative [NF], disorganized [DF], excitement [EF] and anxiety/depression [ADF]). Our TCI-R results showed that patients had different personality dimensions from the control group, but in relatives, these scores were not different from controls. With regard to symptomatology, we highlight the relations observed between harm avoidance (HA) and PANSS NF, and between self-transcendence (ST) and PANSS PF. From a personality traits-genetic factors point of view, schizophrenia and other psychosis may be initially differentiated by temperamental traits such as HA. The so-called characterial traits like ST would be associated with the appearance of psychotic symptoms.
人格维度与精神分裂症患者（SP）的症状维度相关。在本文中，我们研究了功能性精神病患者及其一级亲属（SR）、其他精神病患者（PP）及其一级亲属（PR）以及健康对照者的症状与人格维度之间的关系，以评估这些疾病可能存在的临床维度。使用气质和性格量表（TCI-R）对29名SP、29名SR、18名PP、18名PR和188名对照者进行了评估。使用先前描述的五因素模型（阳性[PF]、阴性[NF]、紊乱[DF]、兴奋[EF]和焦虑/抑郁[ADF]），通过阳性和阴性症状量表（PANSS）评估当前症状。我们的TCI-R结果显示，患者的人格维度与对照组不同，但亲属的这些分数与对照组没有差异。关于症状学，我们强调了在回避伤害（HA）与PANSS NF之间以及自我超越（ST）与PANSS PF之间观察到的关系。从人格特质-遗传因素的角度来看，精神分裂症和其他精神病最初可能通过诸如HA等气质性特质来区分。诸如ST等所谓的性格特质可能与精神病症状的出现有关。
