Department of Neurology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel.
Parkinsonism Relat Disord. 2010 Feb;16(2):101-4. doi: 10.1016/j.parkreldis.2009.07.014. Epub 2009 Aug 20.
Autoimmune polyendocrine syndrome (APS) is a rare disorder. One of the possible associated endocrinopathies in APS is hypoparathyroidism. We describe brain calcifications secondary to hypoparathyroidism in family members with APS and compare clinical manifestations, the extent of brain calcifications on CT scans and the result of PET-FDG scans. We found extensive brain calcifications and striatal hypometabolism in PET-FDG scan in the only symptomatic member of the family, which supports the assumption that extensive brain calcification and the presence of hypometabolism in PET-FDG scan are likely to be found in symptomatic patients with brain calcifications.
自身免疫性多内分泌腺综合征（APS）是一种罕见疾病。APS 可能伴发的内分泌疾病之一是甲状旁腺功能减退症。我们描述了 APS 患者的甲状旁腺功能减退症继发的脑钙化，并比较了 CT 扫描和 PET-FDG 扫描的脑钙化程度和结果。我们发现，在家族中唯一有症状的成员中，存在广泛的脑钙化和纹状体代谢低下，这支持了这样的假设，即广泛的脑钙化和 PET-FDG 扫描中的代谢低下可能在有脑钙化的有症状患者中出现。
