Stechschulte Sarah A, Kirsner Robert S, Federman Daniel G
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Fla, USA.
Am J Med. 2009 Sep;122(9):793-802. doi: 10.1016/j.amjmed.2009.02.029.
Adequate vitamin D status is necessary and beneficial for health, although deficiency plagues much of the world's population. In addition to reducing the risk for bone disease, vitamin D plays a role in reduction of falls, as well as decreases in pain, autoimmune diseases, cancer, heart disease, mortality, and cognitive function. On the basis of this emerging understanding, improving patients' vitamin D status has become an essential aspect of primary care. Although some have suggested increased sun exposure to increase serum vitamin D levels, this has the potential to induce photoaging and skin cancer, especially in patients at risk for these conditions. Vitamin D deficiency and insufficiency can be both corrected and prevented safely through supplementation.
充足的维生素D水平对健康是必要且有益的，尽管维生素D缺乏困扰着世界上许多人口。除了降低患骨病的风险外，维生素D还在减少跌倒风险以及减轻疼痛、自身免疫性疾病、癌症、心脏病、死亡率和改善认知功能方面发挥作用。基于这种新的认识，改善患者的维生素D水平已成为初级保健的一个重要方面。尽管有人建议增加阳光照射以提高血清维生素D水平，但这有可能导致光老化和皮肤癌，尤其是在有这些疾病风险的患者中。通过补充剂可以安全地纠正和预防维生素D缺乏和不足。
