聚合物基磁共振兼容导丝的初步体内研究。

Initial in vivo studies with a polymer-based MR-compatible guide wire.

机构信息

Division of MR Physics, Department of Medical Radiology, University Hospital Basel, Basel, Switzerland.

出版信息

J Vasc Interv Radiol. 2009 Oct;20(10):1384-9. doi: 10.1016/j.jvir.2009.07.001. Epub 2009 Aug 21.

DOI:10.1016/j.jvir.2009.07.001

PMID:19699660

Abstract

The purpose of this study was to evaluate a new polymer-based and magnetic resonance (MR) imaging-compatible guide wire for its application in MR-guided endovascular interventions, particularly for interventional peripheral MR angiography in swine experiments in vivo. A passive device tracking method tailored to the specific conditions of peripheral MR angiography was developed. Near-real-time visualization of the guide wire was accomplished in vivo in the carotid artery, aorta, heart, and iliac arteries of two domestic pigs. Results show great potential for this guide wire in aiding the realization of interventional peripheral MR angiography in humans.

摘要

本研究旨在评估一种新型基于聚合物的磁共振（MR）成像兼容导丝，用于 MR 引导的血管内介入，特别是用于活体猪实验中的介入性外周 MR 血管造影。开发了一种针对外周 MR 血管造影特定条件的被动设备跟踪方法。在两只国内猪的颈动脉、主动脉、心脏和髂动脉中实现了导丝的近实时体内可视化。结果表明，该导丝在辅助实现人类介入性外周 MR 血管造影方面具有很大的潜力。