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血小板功能评估方法。

Methods for evaluation of platelet function.

作者信息

Lindahl Tomas L, Ramström Sofia

机构信息

Department of Clinical and Experimental Medicine, University of Linköping, Sweden.

出版信息

Transfus Apher Sci. 2009 Oct;41(2):121-5. doi: 10.1016/j.transci.2009.07.015. Epub 2009 Aug 21.

Abstract

There are a multitude of platelet function tests available, reflecting the complex nature of the platelet in haemostasis. No simple single test will ever cover all aspects of platelet function. Some tests focus on the aggregation of platelets, for example aggregometry, other on the swelling in response to hypotonic solutions, i.e. the well-known hypotonic shock response, or adhesion or coagulation and clot retraction, for example thromboelastography. In general there is a lack of clinical studies showing a predictive value of analysis of platelet concentrates.

摘要

有多种血小板功能测试方法,这反映了血小板在止血过程中的复杂性质。没有一种简单的单一测试能够涵盖血小板功能的所有方面。一些测试侧重于血小板的聚集,例如血小板聚集测定法;其他测试则关注对低渗溶液的肿胀反应,即著名的低渗休克反应,或血小板的黏附、凝血和血块回缩,例如血栓弹力图。总体而言,缺乏临床研究表明血小板浓缩物分析具有预测价值。

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