通过转座子诱变鉴定鲁氏耶尔森菌中的鞭毛运动基因
Identification of flagellar motility genes in Yersinia ruckeri by transposon mutagenesis.
作者信息
Evenhuis Jason P, Lapatra Scott E, Verner-Jeffreys David W, Dalsgaard Inger, Welch Timothy J
机构信息
National Center for Cool and Cold Water Aquaculture, Agricultural Research Service, U.S. Department of Agriculture, Kearneysville, West Virginia 25430, USA.
出版信息
Appl Environ Microbiol. 2009 Oct;75(20):6630-3. doi: 10.1128/AEM.01415-09. Epub 2009 Aug 21.
Abstract
Here we demonstrate that flagellar secretion is required for production of secreted lipase activity in the fish pathogen Yersinia ruckeri and that neither of these activities is necessary for virulence in rainbow trout. Our results suggest a possible mechanism for the emergence of nonmotile biotype 2 Y. ruckeri through the mutational loss of flagellar secretion.
摘要
在此我们证明，鞭毛分泌对于鱼类病原菌鲁氏耶尔森菌分泌脂肪酶活性的产生是必需的，并且这两种活性对于虹鳟鱼的致病性都不是必需的。我们的结果提示了一种通过鞭毛分泌的突变性丧失而出现鲁氏耶尔森菌非运动生物型2的可能机制。
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