鲁氏耶尔森菌（Yersinia ruckeri）体内柠檬酸摄取相关的 yctCBA 操纵子对于毒力并非必需。
The yctCBA operon of Yersinia ruckeri, involved in in vivo citrate uptake, is not required for virulence.
机构信息
Área de Microbiología, Departamento de Biología Funcional, Facultad de Medicina, IUBA, Universidad de Oviedo, 33006 Oviedo, Asturias, Spain.
出版信息
Appl Environ Microbiol. 2011 Feb;77(3):1107-10. doi: 10.1128/AEM.01808-10. Epub 2010 Dec 3.
Abstract
A three-gene operon, named yctCBA (Yersinia citrate transporter), induced by citrate and repressed by glucose was identified from a previously selected in vivo-induced (ivi) clone in the fish pathogen Yersinia ruckeri. Interestingly, despite being an ivi clone, the drastic growth reduction of the yctC mutant in the presence of citrate, and the relatively high content of this compound in rainbow trout serum, the operon was not required for virulence.
摘要
一个三基因操纵子，命名为 yctCBA（柠檬酸转运蛋白），受柠檬酸诱导，受葡萄糖抑制，从鱼类病原体鲁氏耶尔森氏菌中先前选择的体内诱导（ivi）克隆中鉴定出来。有趣的是，尽管是一个 ivi 克隆，但 yctC 突变体在柠檬酸存在下的生长严重减少，以及虹鳟血清中这种化合物的相对高含量，该操纵子对于毒力不是必需的。
相似文献
1
The yctCBA operon of Yersinia ruckeri, involved in in vivo citrate uptake, is not required for virulence.鲁氏耶尔森菌（Yersinia ruckeri）体内柠檬酸摄取相关的 yctCBA 操纵子对于毒力并非必需。
Appl Environ Microbiol. 2011 Feb;77(3):1107-10. doi: 10.1128/AEM.01808-10. Epub 2010 Dec 3.
2
In vivo monitoring of Yersinia ruckeri in fish tissues: progression and virulence gene expression.鱼类组织中迟钝爱德华氏菌的体内监测：进展和毒力基因表达。
Environ Microbiol Rep. 2013 Feb;5(1):179-85. doi: 10.1111/1758-2229.12030. Epub 2013 Jan 15.
3
A novel cdsAB operon is involved in the uptake of L-cysteine and participates in the pathogenesis of Yersinia ruckeri.一个新的 cdsAB 操纵子参与 L-半胱氨酸的摄取，并参与鲁氏耶尔森菌的发病机制。
J Bacteriol. 2011 Feb;193(4):944-51. doi: 10.1128/JB.01058-10. Epub 2010 Dec 17.
4
The UvrY response regulator of the BarA-UvrY two-component system contributes to Yersinia ruckeri infection of rainbow trout (Oncorhynchus mykiss).巴氏杆菌 UvrY 双组分系统的 UvrY 应答调节子有助于虹鳟鱼（Oncorhynchus mykiss）感染鲁氏耶尔森氏菌。
Arch Microbiol. 2010 Jul;192(7):541-7. doi: 10.1007/s00203-010-0582-8. Epub 2010 May 18.
5
The flagellar master operon flhDC is a pleiotropic regulator involved in motility and virulence of the fish pathogen Yersinia ruckeri.鞭毛主操纵子flhDC是一种多效调节因子，参与鱼类病原菌鲁氏耶尔森菌的运动性和毒力。
J Appl Microbiol. 2017 Mar;122(3):578-588. doi: 10.1111/jam.13374. Epub 2017 Jan 30.
6
The heat sensitive factor (HSF) of Yersinia ruckeri is produced by an alkyl sulphatase involved in sodium dodecyl sulphate (SDS) degradation but not in virulence.鲁氏耶尔森菌的热敏感因子（HSF）由一种参与十二烷基硫酸钠（SDS）降解但不参与毒力的烷基硫酸酯酶产生。
BMC Microbiol. 2014 Sep 30;14:221. doi: 10.1186/s12866-014-0221-7.
7
The yrpAB operon of Yersinia ruckeri encoding two putative U32 peptidases is involved in virulence and induced under microaerobic conditions.鲁氏耶尔森菌编码两种假定的U32肽酶的yrpAB操纵子与毒力有关，并在微需氧条件下被诱导。
Virulence. 2014 Jul 1;5(5):619-24. doi: 10.4161/viru.29363. Epub 2014 May 27.
8
Isolation and analysis of a protease gene with an ABC transport system in the fish pathogen Yersinia ruckeri: insertional mutagenesis and involvement in virulence.鱼类病原菌鲁氏耶尔森菌中一个带有ABC转运系统的蛋白酶基因的分离与分析：插入诱变及与毒力的关系
Microbiology (Reading). 2002 Jul;148(Pt 7):2233-2243. doi: 10.1099/00221287-148-7-2233.
9
In Vivo Bioluminescent Imaging of Yersinia ruckeri Pathogenesis in Fish.鱼类中鲁氏耶尔森菌发病机制的体内生物发光成像
Methods Mol Biol. 2020;2081:69-80. doi: 10.1007/978-1-4939-9940-8_6.
10
Highly sensitive detection and quantification of the pathogen Yersinia ruckeri in fish tissues by using real-time PCR.利用实时 PCR 技术对鱼类组织中的病原菌鲁氏耶尔森菌进行高灵敏度检测和定量分析。
Appl Microbiol Biotechnol. 2012 Oct;96(2):511-20. doi: 10.1007/s00253-012-4328-1. Epub 2012 Aug 7.
引用本文的文献
1
Yersinia ruckeri, the causative agent of enteric redmouth disease in fish.鲁氏耶尔森菌，鱼类肠道红嘴病的病原体。
Vet Res. 2015 Sep 24;46(1):103. doi: 10.1186/s13567-015-0238-4.
本文引用的文献
1
The UvrY response regulator of the BarA-UvrY two-component system contributes to Yersinia ruckeri infection of rainbow trout (Oncorhynchus mykiss).巴氏杆菌 UvrY 双组分系统的 UvrY 应答调节子有助于虹鳟鱼（Oncorhynchus mykiss）感染鲁氏耶尔森氏菌。
Arch Microbiol. 2010 Jul;192(7):541-7. doi: 10.1007/s00203-010-0582-8. Epub 2010 May 18.
2
Yersinia ruckeri genes that attenuate survival in rainbow trout (Oncorhynchus mykiss) are identified using signature-tagged mutants.使用特征标记突变体鉴定了减弱虹鳟（Oncorhynchus mykiss）存活的鲁氏耶尔森氏菌基因。
Vet Microbiol. 2010 Aug 26;144(3-4):399-404. doi: 10.1016/j.vetmic.2010.02.003. Epub 2010 Feb 10.
3
The ZnuABC operon is important for Yersinia ruckeri infections of rainbow trout, Oncorhynchus mykiss (Walbaum).ZnuABC 操纵子对虹鳟鱼（Oncorhynchus mykiss (Walbaum））感染鲁氏耶尔森氏菌（Yersinia ruckeri）非常重要。
J Fish Dis. 2010 Apr;33(4):331-40. doi: 10.1111/j.1365-2761.2009.01125.x. Epub 2010 Jan 12.
4
Identification of flagellar motility genes in Yersinia ruckeri by transposon mutagenesis.通过转座子诱变鉴定鲁氏耶尔森菌中的鞭毛运动基因
Appl Environ Microbiol. 2009 Oct;75(20):6630-3. doi: 10.1128/AEM.01415-09. Epub 2009 Aug 21.
5
A chromosomally located traHIJKCLMN operon encoding a putative type IV secretion system is involved in the virulence of Yersinia ruckeri.一个位于染色体上的traHIJKCLMN操纵子编码一种假定的IV型分泌系统，该操纵子与鲁氏耶尔森菌的毒力有关。
Appl Environ Microbiol. 2009 Feb;75(4):937-45. doi: 10.1128/AEM.01377-08. Epub 2008 Dec 16.
6
Citrate uptake into Pectobacterium atrosepticum is critical for bacterial virulence.柠檬酸盐摄入到黑胫果胶杆菌中对细菌毒力至关重要。
Mol Plant Microbe Interact. 2008 May;21(5):547-54. doi: 10.1094/MPMI-21-5-0547.
7
First report of Yersinia ruckeri biotype 2 in the USA.美国鲁氏耶尔森菌生物型2的首次报告。
J Aquat Anim Health. 2007 Mar;19(1):35-40. doi: 10.1577/H06-011.1.
8
Molecular virulence mechanisms of the fish pathogen Yersinia ruckeri.鱼类病原菌鲁氏耶尔森菌的分子致病机制
Vet Microbiol. 2007 Nov 15;125(1-2):1-10. doi: 10.1016/j.vetmic.2007.06.013. Epub 2007 Jun 22.
9
Identification of genes in Xanthomonas campestris pv. vesicatoria induced during its interaction with tomato.野油菜黄单胞菌疮痂致病变种与番茄互作过程中诱导表达基因的鉴定
J Bacteriol. 2007 Sep;189(17):6359-71. doi: 10.1128/JB.00320-07. Epub 2007 Jun 15.
10
Characterization of citrate utilization in Corynebacterium glutamicum by transcriptome and proteome analysis.通过转录组和蛋白质组分析对谷氨酸棒杆菌中柠檬酸盐利用的表征
FEMS Microbiol Lett. 2007 Aug;273(1):109-19. doi: 10.1111/j.1574-6968.2007.00793.x. Epub 2007 Jun 7.
Zotero 插件