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使用周围神经场刺激(PNFS)成功治疗顽固性带状疱疹后神经痛(PHN)。

Successful treatment of an intractable postherpetic neuralgia (PHN) using peripheral nerve field stimulation (PNFS).

作者信息

Mishra Seema, Bhatnagar Sushma

机构信息

Department of Anaesthesiology, Dr. BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Am J Hosp Palliat Care. 2010 Feb;27(1):59-62. doi: 10.1177/1049909109342089. Epub 2009 Aug 21.

Abstract

Postherpetic neuralgia (PHN) is a chronic neuropathic pain syndrome that arises as a sequel of herpes zoaster eruption. The treatment of postherpetic neuralgia is medically challenging and often frustrating in some situation as the exact mechanism of neuralgia is poorly understood and multiple and complex pathophysiology is postulated requiring poly pharmacy, which itself leads to many side effects. Here, we present a successful management of supra-orbital PHN using peripheral nerve field stimulation (PNFS), which was refractory to the commonly used pharmacological treatment. After successful trial stimulation, permanent stimulator was placed successfully, patient medication were tapered off within 2 weeks. At present, patient is in 8-week poststimulation with excellent pain relief, without any side effect.

摘要

带状疱疹后神经痛(PHN)是一种慢性神经病理性疼痛综合征,是带状疱疹爆发后的后遗症。由于神经痛的确切机制尚不清楚,且推测存在多种复杂的病理生理学,需要联合用药,而联合用药本身会导致许多副作用,因此带状疱疹后神经痛的治疗在医学上具有挑战性,在某些情况下往往令人沮丧。在此,我们展示了一例使用周围神经场刺激(PNFS)成功治疗眶上带状疱疹后神经痛的病例,该患者对常用的药物治疗无效。在成功进行试验性刺激后,成功植入了永久性刺激器,患者的药物在2周内逐渐减量。目前,患者在刺激后8周,疼痛缓解良好,无任何副作用。

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