Lodha A, Haran M
Maimonides Medical Center, Brooklyn, NY 11219, USA.
Int J STD AIDS. 2009 Sep;20(9):666-7. doi: 10.1258/ijsa.2008.008451.
We report a case of a 45-year-old patient with a history of cryptococcal meningitis who was started on antiretroviral therapy. The patient presented four months later with complaints of fever and memory loss. Lumbar puncture revealed positive cryptococcal antigen and therefore the patient was treated for recurrent cryptococcal meningitis. Unfortunately, the patient did not improve even after two weeks. The diagnosis of immune reconstitution was made at this time and steroids were started. The patient showed remarkable improvement.
我们报告一例45岁有隐球菌性脑膜炎病史的患者，该患者开始接受抗逆转录病毒治疗。四个月后，患者出现发热和记忆力减退的症状。腰椎穿刺显示隐球菌抗原阳性，因此该患者因复发性隐球菌性脑膜炎接受治疗。不幸的是，即使经过两周治疗，患者仍无改善。此时诊断为免疫重建，并开始使用类固醇治疗。患者病情显著改善。
