羟甲异丁肾上腺素与地高辛对轻至中度心力衰竭患者的比较疗效。意大利羟甲异丁肾上腺素多中心研究小组。
Comparative effects of xamoterol and digoxin in patients with mild to moderate heart failure. The Italian Xamoterol Multicenter Research Group.
出版信息
Eur Heart J. 1990 Apr;11 Suppl A:50-1. doi: 10.1093/eurheartj/11.suppl_a.50.
Abstract
Xamoterol, 200 mg b.d. was compared with digoxin 0.125 mg b.d. or t.d. in a 3-month double-blind trial in 178 patients with mild to moderate heart failure. Xamoterol and digoxin both significantly increased exercise duration, but greater changes were observed with xamoterol. Xamoterol also improved quality of life to a greater degree than digoxin, and was better tolerated.
摘要
在一项针对178例轻至中度心力衰竭患者的为期3个月的双盲试验中，将每日两次服用200毫克的昔莫洛尔与每日两次或三次服用0.125毫克的地高辛进行了比较。昔莫洛尔和地高辛均显著增加了运动持续时间，但昔莫洛尔的变化更大。昔莫洛尔在改善生活质量方面也比地高辛程度更大，且耐受性更好。
Zotero 插件