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牛津三期内侧单髁膝关节置换早期生存率降低的相关因素。

Factors associated with reduced early survival in the Oxford phase III medial unicompartment knee replacement.

作者信息

Kuipers Bart M, Kollen Boudewijn J, Bots Peter C Kaijser, Burger Bart J, van Raay Jos J A M, Tulp Niek J A, Verheyen Cees C P M

机构信息

Department of Orthopaedic Surgery, Isala Clinics, Zwolle, The Netherlands.

出版信息

Knee. 2010 Jan;17(1):48-52. doi: 10.1016/j.knee.2009.07.005. Epub 2009 Aug 28.

Abstract

The aim of this study was to determine the prognostic value of preoperative patellofemoral osteoarthritis, BMI and age for implant survival of unicompartmental knee arthroplasty (UKA) performed in patients meeting strict admission criteria. The data and radiographs of 437 unilateral Oxford phase III procedures (Biomet, Bridgend, UK) were analysed. All procedures were carried out or supervised by 13 specialised knee surgeons in three different hospitals. The study group comprised 437 patients with a median follow of 2.6 years (0.1-7.9). The cumulative standard case survival rate at 5 years, when there were still 101 patients at risk, was 84.7% (CI-95%: 80.1-89.3%). Young age (<60 years) was associated with a 2.2-fold increased adjusted risk of revision (CI: 1.08-4.43; p=0.03). The preoperative presence of radiological features of patellofemoral osteoarthritis was associated with a 0.3-fold reduced adjusted risk of revision (CI: 0.11-0.89; p=0.03). BMI>30 kg/m(2), gender, the surgeon performing the operation (either as an individual or categorised by annual surgical UKA caseload, i.e., more or less than 10 UKAs) and the hospital in which surgery took place did not predict implant survival of UKA. We conclude that young patients (<60 years) experience an increased early risk of revision for UKA when compared to older patients (>60 years). Obesity (BMI>30 kg/m(2)) and preoperative patellofemoral osteoarthritis are not associated with a decreased implant survival and therefore should not be considered risk factors in this context.

摘要

本研究旨在确定术前髌股关节炎、体重指数(BMI)和年龄对符合严格入组标准患者进行单髁膝关节置换术(UKA)植入物存活情况的预后价值。分析了437例单侧牛津三期手术(英国布里真德市的Biomet公司)的数据和X线片。所有手术均由三家不同医院的13名专业膝关节外科医生实施或监督。研究组包括437例患者,中位随访时间为2.6年(0.1 - 7.9年)。在仍有101例患者处于风险期时,5年的累积标准病例存活率为84.7%(95%置信区间:80.1 - 89.3%)。年轻患者(<60岁)调整后的翻修风险增加2.2倍(置信区间:1.08 - 4.43;p = 0.03)。术前存在髌股关节炎的放射学特征与调整后的翻修风险降低0.3倍相关(置信区间:0.11 - 0.89;p = 0.03)。BMI>30 kg/m²、性别、实施手术的外科医生(作为个体或按每年UKA手术病例数分类,即多于或少于10例UKA)以及手术所在医院均不能预测UKA植入物的存活情况。我们得出结论,与老年患者(>60岁)相比,年轻患者(<60岁)UKA早期翻修风险增加。肥胖(BMI>30 kg/m²)和术前髌股关节炎与植入物存活率降低无关,因此在此背景下不应被视为风险因素。

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