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临床和技术因素对单髁膝关节置换术结果的影响:944 例膝关节回顾性多中心研究。

Clinical and technical factors influencing outcomes of unicompartmental knee arthroplasty: Retrospective multicentre study of 944 knees.

机构信息

Département de chirurgie orthopédique, CHU de Caen, avenue de la Côte-de-Nacre, Caen, France.

出版信息

Orthop Traumatol Surg Res. 2013 Jun;99(4 Suppl):S227-34. doi: 10.1016/j.otsr.2013.02.002. Epub 2013 Apr 25.

Abstract

INTRODUCTION

Unicompartmental knee arthroplasty (UKA) is reserved for osteoarthritis confined to a single femoro-tibial compartment with an intact anterior cruciate ligament. UKA remains controversial. The objective of this retrospective multicentre study in a large sample was to assess the influence of age, sex, body mass index (BMI), patellofemoral involvement, and implant design on functional outcomes and prosthesis survival rates.

MATERIAL AND METHODS

Nine hundred and forty-four patients who underwent UKA at centres located in western France between 1988 and 2008 were re-evaluated. The IKS scores and KOOS were determined. Prosthesis survival according to various factors was assessed using the Kaplan-Meier method.

RESULTS

A clinical evaluation was performed in 720 cases after a mean follow-up of 62 months. The IKS function score improved by 23.6 points in men and 17.3 points in women (P=0.007). Ten-year prosthesis survival was 83.7% overall; 79% in women versus 87% in men (P<0.01); and 76.7% in patients younger than 70 years versus 88.3% in those 70 years or over (P<0.01). BMI had no significant influence on prosthesis survival. No significant differences between clinical outcomes or prosthesis survival were found across implant design categories.

DISCUSSION

The retrospective design and large number of centres and surgeons mandate caution when interpreting our results. Subgroup sizes were too small for an analysis of factors such as anterior cruciate ligament deficiency, BMI>40 kg/m(2), or cementless implant.

LEVEL OF EVIDENCE

Level IV, retrospective study.

摘要

介绍

单髁膝关节置换术(UKA)仅适用于伴有完整前交叉韧带的单间室骨关节炎患者。UKA 仍存在争议。本研究为回顾性多中心研究,纳入了大量患者,旨在评估年龄、性别、体重指数(BMI)、髌股关节受累情况和假体设计对功能结果和假体生存率的影响。

材料和方法

对 1988 年至 2008 年在法国西部中心接受 UKA 的 944 例患者进行了重新评估。评估了 IKS 评分和 KOOS。使用 Kaplan-Meier 法评估各种因素对假体生存率的影响。

结果

在平均随访 62 个月后,720 例患者进行了临床评估。男性的 IKS 功能评分提高了 23.6 分,女性提高了 17.3 分(P=0.007)。总体 10 年假体生存率为 83.7%;女性为 79%,男性为 87%(P<0.01);年龄<70 岁的患者为 76.7%,年龄≥70 岁的患者为 88.3%(P<0.01)。BMI 对假体生存率无显著影响。不同假体设计类别之间的临床结果或假体生存率无显著差异。

讨论

回顾性设计和大量中心和外科医生的参与使得我们在解释结果时需要谨慎。对于前交叉韧带缺失、BMI>40 kg/m2 或非骨水泥假体等因素的分析,亚组规模太小。

证据等级

IV 级,回顾性研究。

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