State Key Laboratory of Applied Organic Chemistry and Institute of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
Colloids Surf B Biointerfaces. 2009 Dec 1;74(2):511-5. doi: 10.1016/j.colsurfb.2009.07.042. Epub 2009 Aug 8.
The crosslinked polymeric nanocapsules with inner diameter of about 20-50nm were prepared successfully by the post-treatment of the poly(methyl acrylate) (PMA) brushes grafted silica nanoparticles (SN-PMA) produced with the surface-initiated atom transfer radical polymerization (SI-ATRP) technique. The PMA chains grafted were modified with amino groups by being treated with ethanediamine (EDA). Then the silica nanoparticles (SN) templates were removed by being etched with hydrofluoric acid (HF) to produce the crosslinked polymeric nanocapsules after the aminated poly(methyl acrylate) (APMA) chains on the SN templates were crosslinked with hexamethylene diisocyanate (HDI). Transmission electron microscopy (TEM) analyses were used to estimate the size of the polymeric nanocapsules.
成功地通过后处理技术制备了交联聚合物纳米胶囊，其内径约为 20-50nm。该纳米胶囊是通过表面引发原子转移自由基聚合（SI-ATRP）技术制备的接枝有聚甲基丙烯酸酯（PMA）刷的二氧化硅纳米粒子（SN-PMA）制得。用乙二胺（EDA）处理接枝的 PMA 链，将其改性为氨基。然后用氢氟酸（HF）刻蚀去除二氧化硅纳米粒子（SN）模板，在 SN 模板上的氨基化聚甲基丙烯酸酯（APMA）链与己二异氰酸酯（HDI）交联后，得到交联聚合物纳米胶囊。使用透射电子显微镜（TEM）分析来估计聚合物纳米胶囊的尺寸。
