Ari Hasan, Ari Selma, Koca Vedat, Bozat Tahsin
Department of Cardiology, Bursa Postgraduate Hospital, Bursa, Turkey.
Turk Kardiyol Dern Ars. 2009 Jun;37(4):266-8.
Hypocalcaemia is a rare cause of reversible heart failure. We present a 27-year-old man who had severe heart failure unresponsive to medical therapy. He had vitamin D-resistant rickets for which he had received replacement therapy with vitamin D and calcium until age 20, but he discontinued treatment for the past seven years. Severe hypocalcemia was detected. Echocardiography showed left ventricular dilatation, global hypokinesia (ejection fraction 25%), and mitral and tricuspid regurgitation of grades 3 and 2, respectively. After calcium and vitamin D supplementation, his symptoms showed rapid improvement. At nine months, myocardial dysfunction improved fully. Hypocalcemia should be considered among the causes of heart failure unresponsive to medical treatment.
低钙血症是导致可逆性心力衰竭的罕见原因。我们报告一名27岁男性,他患有严重心力衰竭,药物治疗无效。他患有维生素D抵抗性佝偻病,在20岁之前一直接受维生素D和钙的替代治疗,但在过去七年中停止了治疗。检测到严重低钙血症。超声心动图显示左心室扩张、整体运动减弱(射血分数25%),二尖瓣和三尖瓣反流分别为3级和2级。补充钙和维生素D后,他的症状迅速改善。九个月时,心肌功能障碍完全改善。对于药物治疗无效的心力衰竭病因,应考虑低钙血症。