Lady Reading Hospital Peshawar, Pakistan.
Naas General Hospital, Ireland.
J Ayub Med Coll Abbottabad. 2023 Oct-Dec;35(Suppl 1)(4):S810-S812. doi: 10.55519/JAMC-S4-12192.
Dilated cardiomyopathy is characterized by dilation and enlargement of one or both ventricles with reduced systolic function. Calcium plays a key role in myocardial contraction. Hypocalcaemia can lead to a decrease in contraction, left ventricular systolic dysfunction, and heart failure with reduced ejection fraction (EF). Hypocalcaemia is a rare reversible cause of dilated cardiomyopathy. The author presents a case who presented with complaints of shortness of breath on exertion, orthopnoea, paroxysmal nocturnal dyspnoea, numbness and crampy muscular pains. He had a high JVP, systolic murmur on auscultation, hepatomegaly, pedal oedema and crackles on chest auscultation. His ECG showed sinus rhythm with prolonged QT interval. His echocardiography showed dilated cardiomyopathy with reduced ejection fraction, moderate mitral regurgitation and mild tricuspid regurgitation. His Calcium levels and PTH levels were both low. He was treated with ionotrophes, diuretics, vitamin D and calcium supplements, including both intravenous and oral. With the correction of calcium levels, he was weaned off the ionotrophic support and his ejection fraction improved. Calcium levels if low should be corrected in patients with dilated cardiomyopathy.
扩张型心肌病的特征是一个或两个心室扩张和增大,伴有收缩功能降低。钙在心肌收缩中起着关键作用。低钙血症可导致收缩力下降、左心室收缩功能障碍以及射血分数降低的心力衰竭。低钙血症是扩张型心肌病罕见的可逆转病因。作者报告了一例患者,其表现为活动时呼吸困难、端坐呼吸、阵发性夜间呼吸困难、麻木和痉挛性肌肉疼痛。他的颈静脉压高,听诊有收缩期杂音,肝肿大,下肢水肿,胸部听诊有爆裂音。他的心电图显示窦性心律伴 QT 间期延长。他的超声心动图显示扩张型心肌病,射血分数降低,中度二尖瓣反流和轻度三尖瓣反流。他的钙和甲状旁腺激素水平均低。他接受了正性肌力药、利尿剂、维生素 D 和钙补充剂治疗,包括静脉和口服。随着钙水平的纠正,他逐渐停用了正性肌力支持,射血分数也得到了改善。扩张型心肌病患者如果血钙水平低,应予以纠正。