Schmid P
Sonderkrankenanstalt für Herz-Kreislauferkrankungen, Versicherungsanstalt öffentlich Bediensteter (BVA), Bad Schallerbach.
Wien Med Wochenschr. 1990 Apr 15;140(6-7):184-8.
The application of beta-blocking agents in endurance sports leads to deterioration of physical capacity because of negative influence of hemodynamics and metabolism. In sports with modest dynamic but high psychological strain it leads to an increase of physical capacity and decrease of stress caused by competition. The present paper summarizes changes in ski jumping, flying, motor car racing, parachute jumping, bob running and shooting. Significant decreases of heart rate, modest decreases in blood pressure as well as a reduction of occasionally appearing extrasystoles are found. Levels of glucose and lactate as well as cholesterol and triglycerides remain unchanged during beta-blockade, as do free fatty acids and free glycerol with placebo under beta-adrenolyse. Whereas ski and parachute jumpers display psychologic stress, bob runners and sport shooters were positively influenced. As a possible reason for an increased physical capacity after sympathicolysis, changes of cardiovascular parameters as well as central influences are conceivable. The application of beta-blocking agents should be regarded as "doping" because of the increases of physical capacity and should be avoided in healthy sportsmen.
β受体阻滞剂应用于耐力运动时,由于对血液动力学和代谢产生负面影响,会导致体能下降。在动态适度但心理压力较大的运动中,它会使体能增加,并减轻比赛造成的压力。本文总结了在跳台滑雪、飞行、赛车、跳伞、有舵雪橇滑行和射击运动中的变化情况。发现心率显著下降,血压略有下降,偶尔出现的早搏也减少。在β受体阻滞剂治疗期间,血糖、乳酸以及胆固醇和甘油三酯水平保持不变,在β肾上腺素能阻断下使用安慰剂时,游离脂肪酸和游离甘油水平也保持不变。跳台滑雪运动员和跳伞运动员会表现出心理压力,而有舵雪橇滑行运动员和射击运动员则受到了积极影响。作为交感神经阻滞术后体能增加的一个可能原因,可以想象心血管参数的变化以及中枢影响。由于体能增加,β受体阻滞剂的应用应被视为“使用兴奋剂”,健康运动员应避免使用。