Azuma Kotaro
Department of Geriatric Medicine, University of Tokyo Hospital.
Clin Calcium. 2009 Sep;19(9):1345-52.
Diagnosis and treatment of osteoporosis are evolving from BMD (bone mineral density) dependent manner to bone quality conscious manner. However, clinical methods to evaluate bone quality of diabetic patients have not been established yet. Therefore, many potentially osteoporotic patients with diabetes are not recognized as high fracture risk patients under the current therapeutic guideline of osteoporosis. On the other hand, some drugs for osteoporosis affect pathophysiology of diabetes. In the future, it is possible that drugs for osteoporosis are chosen according to the diabetic state of each patient.
骨质疏松症的诊断和治疗正从依赖骨密度(BMD)的方式向注重骨质量的方式演变。然而,评估糖尿病患者骨质量的临床方法尚未确立。因此,在目前的骨质疏松症治疗指南下,许多潜在的糖尿病骨质疏松症患者未被视为高骨折风险患者。另一方面,一些骨质疏松症药物会影响糖尿病的病理生理。未来,有可能根据每位患者的糖尿病状况来选择骨质疏松症药物。