Oller Adriana R, Cappellini Danielle, Henderson Rayetta G, Bates Hudson K
NiPERA, Durham, NC 27713, USA.
J Environ Monit. 2009 Sep;11(9):1697-9. doi: 10.1039/b909157b. Epub 2009 Aug 14.
Leaching in ammonium citrate has been extensively used to assess the fraction of water-soluble nickel compounds present in nickel producing and using workplace aerosols. Leaching in ammonium citrate according to the first step of the Zatka protocol was found to overestimate the water-soluble nickel fraction by more than ten-fold compared to synthetic lung fluid (37 degrees C), when nickel carbonate and subsulfide were present. These results suggest that exposure matrices based on this method should be reexamined. Leaching studies of refinery particles are needed to further clarify this important issue.
柠檬酸铵浸出法已被广泛用于评估镍生产和使用工作场所气溶胶中水溶性镍化合物的含量。当存在碳酸镍和次硫化镍时，按照扎特卡协议第一步进行的柠檬酸铵浸出法，与合成肺液（37摄氏度）相比，高估了水溶性镍含量十多倍。这些结果表明，基于该方法的暴露模型应重新审视。需要对炼油厂颗粒进行浸出研究，以进一步阐明这一重要问题。
