Canadian Light Source Inc., Saskatoon, SK, Canada.
Environ Sci Process Impacts. 2015 May;17(5):922-31. doi: 10.1039/c4em00603h. Epub 2015 Apr 10.
There is a pressing need to further develop speciation knowledge of Ni workplace aerosols as the Zatka sequential extraction method used until now to speciate workplace Ni exposures has limitations. Here we compare the Zatka and XANES methods and evaluate XANES spectroscopy as a more appropriate and accurate technique for identifying nickel species in workplace aerosols. XANES spectroscopy is capable of identifying unique Ni species in the unaltered samples. Our findings indicate some significant departures in speciation assignment between the Zatka and XANES methods. In particular, the Zatka method can overestimate the soluble Ni fraction and it may underestimate the sulphidic and metallic fractions in some samples. Of particular importance, XANES is able to identify component sulphidic species. This information can lead to more accurate exposure matrices and more refined epidemiological analysis of respiratory cancer causation in sulphidic Ni processing.
目前迫切需要进一步发展镍工作场所气溶胶的物种形成知识，因为迄今为止用于物种形成的 Zatka 顺序提取方法存在局限性。在这里，我们比较了 Zatka 和 XANES 方法，并评估了 XANES 光谱作为一种更合适和准确的技术，用于识别工作场所气溶胶中的镍物种。XANES 光谱能够在未经改变的样品中识别独特的镍物种。我们的研究结果表明，Zatka 和 XANES 方法在物种形成分配上存在一些显著差异。特别是，Zatka 方法可能高估可溶性镍部分，并且在某些样品中可能低估硫化物和金属部分。特别重要的是，XANES 能够识别组成硫化物的物种。这些信息可以提供更准确的暴露矩阵，并对硫化镍加工过程中呼吸癌发病原因进行更精细的流行病学分析。
