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血清(1→3)β-D-葡聚糖作为艾滋病患者肺孢子菌肺炎诊断的非侵入性辅助标志物。

Serum (1-->3) beta-D-glucan as a noninvasive adjunct marker for the diagnosis of Pneumocystis pneumonia in patients with AIDS.

作者信息

Watanabe Tamayo, Yasuoka Akira, Tanuma Junko, Yazaki Hirohisa, Honda Haruhito, Tsukada Kunihisa, Honda Miwako, Gatanaga Hiroyuki, Teruya Katsuji, Kikuchi Yoshimi, Oka Shinichi

机构信息

AIDS Clinical Center, International Medical Center of Japan, Tokyo, Japan.

出版信息

Clin Infect Dis. 2009 Oct 1;49(7):1128-31. doi: 10.1086/605579.

Abstract

High serum (1-->3) beta-D-glucan levels are described in patients with Pneumocystis pneumonia (PCP). We evaluated the diagnostic value of beta-D-glucan in 111 patients with AIDS who had PCP and confirmed its usefulness. However, it does not correlate with disease severity and is not suitable for monitoring response to treatment.

摘要

肺孢子菌肺炎(PCP)患者血清(1→3)β-D-葡聚糖水平较高。我们评估了β-D-葡聚糖在111例患有PCP的艾滋病患者中的诊断价值,并证实了其有效性。然而,它与疾病严重程度无关,不适用于监测治疗反应。

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