Duan Gang, Xu Yi-kai, Deng Hai-jun, Huang Chan-tao
Huiqiao Department, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2009 Aug;29(8):1643-6.
To investigate the features of intraductal papilloma of the breast in mammography and magnetic resonance imaging (MRI) and assess the diagnostic values of the two imaging modalities.
Fifteen patients with intraductal papilloma of the breast confirmed surgically and pathologically underwent X-ray examination of the breast, and 11 of them also received enhanced MRI. The imaging findings by mammography and MRI were compared.
Enhanced MRI clearly displayed the location and morphology of the intraductal papilloma, and 7 patients showed smooth tumor margins and 2 showed irregular margins. On T(1)WI, the lesions were isointense or slightly hypointense, and appeared isointense or slightly hyperintense on T(2)WI. Some of the intraductal papillomas were seen encapsulated in the dilated ductal. The varying enhancement features of the lesions increased the difficulty in distinguishing from carcinoma. Mammography identified intraductal papillomas only in 2 of the 15 cases (13%) with lesion feature similar to that found by MRI. Fine cluster calcification was found in 1 case.
MRI can more accurately define the location of the lesion than X-ray. In spite of some resemblance in the MRI findings between intraductal papillomas and breast carcinoma, MRI still serves as a useful diagnostic modality for intraductal papilloma that shows some characteristic findings.
探讨乳腺导管内乳头状瘤在乳腺钼靶摄影及磁共振成像(MRI)中的表现特征,并评估这两种成像方式的诊断价值。
15例经手术及病理证实的乳腺导管内乳头状瘤患者接受了乳腺X线检查,其中11例还接受了增强MRI检查。比较钼靶摄影和MRI的影像学表现。
增强MRI能清晰显示导管内乳头状瘤的位置及形态,7例肿瘤边缘光滑,2例边缘不规则。在T(1)WI上,病变呈等信号或稍低信号,在T(2)WI上呈等信号或稍高信号。部分导管内乳头状瘤可见被扩张的导管包绕。病变的不同强化特征增加了与癌鉴别的难度。钼靶摄影仅在15例中的2例(13%)发现导管内乳头状瘤,其病变特征与MRI所见相似。1例发现细颗粒状钙化。
MRI比X线能更准确地确定病变位置。尽管导管内乳头状瘤与乳腺癌在MRI表现上有一些相似之处,但MRI仍是显示某些特征性表现的导管内乳头状瘤的一种有用诊断方法。