Radiology Department, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Cancer Rep (Hoboken). 2018 Dec;1(4):e1136. doi: 10.1002/cnr2.1136. Epub 2018 Sep 24.
With the increasing use of image-guided biopsy, more breast intraductal papillomas are found than ever. Most intraductal papillomas are small, ranging from several milimeters to 2 cm.
We described a case of giant intraductal papilloma of breast in a 19-year-old girl with nipple bloody discharge and rapid growth. Magnetic resonance imaging diagnostic evaluation and pathologic correlation along with review of relevant literatures are documented. The lesion was characterized by presence of mixture of cystic and solid component with cystic component occupying a large space. The solid component showed morphologic, kinetic, and diffusion weighted imaging features suggestive of malignancy. Infarction with no enhancement was noted. Cystic compartments contained hemorrhage with fluid-fluid level formation. The patient undertook lumpectomy.
For a giant breast tumor with mixed solid and cystic component, intraductal papilloma should be considered in the differential diagnosis.
随着影像引导活检的应用日益增多,现在发现的乳腺导管内乳头状瘤比以往任何时候都多。大多数导管内乳头状瘤较小,直径从几毫米到 2 厘米不等。
我们描述了一例 19 岁女孩因乳头血性溢液和快速生长而患有巨大乳腺导管内乳头状瘤的病例。记录了磁共振成像诊断评估和病理相关性以及相关文献复习。病变的特点是存在囊实性混合成分,囊性成分占据较大空间。实性成分表现出形态、动力学和扩散加权成像特征提示恶性。可见无强化的梗死。囊性隔室含有含液-液平面形成的出血。患者接受了肿块切除术。
对于混合实性和囊性成分的巨大乳腺肿瘤,应考虑导管内乳头状瘤作为鉴别诊断。