Department of Ophthalmology, Corneal Dystrophy Research Institute, Yonsei University, College of Medicine, Seoul, Korea.
Br J Ophthalmol. 2010 Mar;94(3):341-5. doi: 10.1136/bjo.2009.164525. Epub 2009 Sep 1.
To evaluate the use of Fourier-domain optical coherence tomography (FD-OCT) in the selection and planning of surgical procedures to treat GCD2 (granular corneal dystrophy type 2).
An RTVue-100 FD-OCT (Optovue, Fremont, California) was used to determine the size, depth and location of deposits in six patients with homozygous or heterozygous GCD2.
The RTVue-100 FD-OCT revealed the depth of the deposits quite precisely, allowing the determination of the appropriate depth of PTK (phototherapeutic keratectomy) and the appropriate selection of lamellar versus penetrating keratoplasty as the procedure of choice. In each case, visually significant opacities were adequately removed or would be removed.
FD-OCT provides useful information for the selection and planning of surgical procedures to remove corneal opacities in patients with GCD2.
评估傅里叶域光学相干断层扫描（FD-OCT）在选择和规划治疗 GCD2（颗粒状角膜营养不良 2 型）手术中的应用。
使用 RTVue-100 FD-OCT（Optovue，加利福尼亚州弗里蒙特）来确定 6 名纯合子或杂合子 GCD2 患者的沉积物的大小、深度和位置。
RTVue-100 FD-OCT 非常精确地显示了沉积物的深度，允许确定适当的 PTK（光动力角膜切削术）深度，并适当选择板层角膜移植术与穿透性角膜移植术作为首选手术。在每种情况下，明显的混浊都得到了充分的去除或将要去除。
FD-OCT 为去除 GCD2 患者角膜混浊的手术选择和规划提供了有用的信息。
