Department of Diagnostic Imaging, Interventional Radiology, Molecolar Imaging and Radiotherapy, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.
Cardiovasc Intervent Radiol. 2009 Nov;32(6):1146-53. doi: 10.1007/s00270-009-9690-8.
Our objective was to evaluate the possible role of endovascular recanalization of occluded native artery after a failed bypass graft in the case of either acute or chronic limb-threatening ischemia otherwise leading to amputation. In a single-center retrospective clinical analysis, from January 2004 to March 2007 we collected 31 consecutive high-surgical-risk patients (32 limbs) with critical limb ischemia following late ([30 days after surgery) failure of open surgery bypass graft reconstruction. All patients deemed unfit for surgery underwent tentative endovascular recanalization of the native occluded arterial tract. The mean follow-up period was 24 (range, 6-42) months. Technical success was achieved in 30 (93.7%) of 32 limbs. The cumulative primary assisted patency calculated by Kaplan-Meyer analysis was 92% and 88%, respectively, at 12 and 24 months. The limb salvage rate approached 90% at 30 months. In conclusion, our experience shows the feasibility of occluded native artery endovascular recanalization after a failed bypass graft, with optimal results in terms of midterm arterial patency and limb salvage. Our opinion is that successful recanalization of the arterial tract previously considered unsuitable for endovascular approach is allowed by improved competency and experience of vascular specialists, as well as the advances made in catheter and guidewire technology. This group of patients would previously have been relegated to repeat bypass grafts, with their inherently inferior patency and recognized added technical demands. We recognize previous surgical native artery disconnection and lack of pedal runoff to be the main cause of technical failure.
我们的目的是评估在急性或慢性肢体威胁性缺血的情况下,对闭塞的自体动脉进行血管内再通治疗的可能性,这种情况可能会导致需要截肢。在单中心回顾性临床分析中,我们收集了 2004 年 1 月至 2007 年 3 月间 31 例高手术风险的患者(32 条肢体),这些患者在开放手术旁路移植重建后出现晚期(手术后 30 天)失败,出现严重肢体缺血。所有被认为不适合手术的患者都接受了尝试性的自体闭塞动脉腔内再通治疗。平均随访时间为 24 个月(范围为 6-42 个月)。32 条肢体中有 30 条(93.7%)达到了技术上的成功。通过 Kaplan-Meier 分析计算的累积一期辅助通畅率分别为 12 个月和 24 个月时的 92%和 88%。30 个月时的肢体存活率接近 90%。总之,我们的经验表明,在失败的旁路移植后,闭塞的自体动脉血管内再通是可行的,在中期动脉通畅率和肢体存活率方面有良好的效果。我们认为,由于血管专家的能力和经验的提高,以及导管和导丝技术的进步,使得以前认为不适合血管内治疗的动脉通道的成功再通成为可能。这组患者以前可能会被降级到重复旁路移植,因为它们本身的通畅性较差,并且技术要求也较高。我们认识到以前的手术中自体动脉的断开和缺乏足背血流是技术失败的主要原因。