Harland C C, Balsitis M, Millard L G
Department of Dermatology, University Hospital, Nottingham, England.
Acta Derm Venereol. 1990;70(3):251-3.
A 37-year-old woman presented with an aggressive leukaemic form of small T-cell Sézary syndrome. Despite this unusually malignant variant of the disease, there was a dramatic response to a modified Winkelmann regimen of chlorambucil and prednisolone, and a useful, sustained remission of 7 months. The Winkelmann regimen remains an important and relatively non-toxic chemotherapeutic option for palliation of advanced Sézary syndrome.
