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[从事繁重脑力劳动的缺血性心脏病青年患者的高脂蛋白血症类型]

[Types of hyperlipoproteinemia in young persons with ischemic heart diseases engaged in strenuous mental work].

作者信息

Krivoruchenko I V, Nikul'cheva N G, Kukuĭ L M, Bermiakova A S

出版信息

Kardiologiia. 1977 Jun;17(6):74-9.

PMID:197287
Abstract

The results subsequent to an examination of 250 males aged 30-47 suffering from ischemic heart disease and doing strenous mental work are presented. Two variants were used in phenotyping: the first was based on not too high criteria for the cholesterol and triglycerides level (250 and 140 mg%, respectively), the second one having as a groundwork upper limits of the normal value estimated by the authors (250 and 190 mg%, respectively). It was found that, depending upon the actual value of the upper normal limit for triglycerides hyperlipidemia is demonstrable in 64 or 56% of the males. Of most frequent occurrence were the II and IV types of hyperlipoproteinemia with the latter type prevailing in both variants. Most patients with ischemic heart disease demonstrated a fall of alpha-lipoproteins, as ascertained by their separation through disc-electrophoresis in polyacrylamide gel.

摘要

本文展示了对250名年龄在30至47岁之间、患有缺血性心脏病且从事高强度脑力劳动的男性进行检查后的结果。表型分析采用了两种变体:第一种基于胆固醇和甘油三酯水平的标准不太高(分别为250和140毫克%),第二种以作者估计的正常值上限为基础(分别为250和190毫克%)。结果发现,根据甘油三酯正常上限的实际值,64%或56%的男性存在高脂血症。最常见的是II型和IV型高脂蛋白血症,在两种变体中均以后者为主。通过聚丙烯酰胺凝胶圆盘电泳分离确定,大多数缺血性心脏病患者的α脂蛋白水平下降。

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