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主动脉弓手术后 ICU 住院时间延长的术前和术中危险因素。

Preoperative and intraoperative risk factors for prolonged intensive care unit stay after aortic arch surgery.

机构信息

Department of Anesthesiology, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

J Cardiothorac Vasc Anesth. 2009 Dec;23(6):789-94. doi: 10.1053/j.jvca.2009.05.028. Epub 2009 Sep 3.

DOI:10.1053/j.jvca.2009.05.028
PMID:19729322
Abstract

OBJECTIVE

The present study was performed to evaluate preoperative and intraoperative risk factors for prolonged intensive care unit (ICU) stay after aortic arch surgery.

DESIGN

A retrospective study. Prolonged ICU stay was defined as >5 days (120 hours).

SETTING

Cardiovascular operating rooms and the ICU.

PARTICIPANTS

Adults requiring aortic arch surgery with deep hypothermic circulatory arrest plus antegrade selective cerebral perfusion.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

After 11 patients who underwent 1-stage total or subtotal aortic replacement were excluded, 298 patients were enrolled in the study. The average age of patients was 44.9 +/- 10.7 years with male predominance (74.8%). Sixty-one patients (20.5%) stayed longer than 5 days in the ICU. Univariate analyses found age, body mass index, New York Heart Association classification, preoperative serum creatinine, creatinine clearance, emergency, inotropes, cardiopulmonary bypass time, myocardial ischemia time, and fresh-frozen plasma transfused intraoperatively were significantly associated with prolonged ICU stay (p < 0.05). Independent risk factors for prolonged ICU stay were found to be New York Heart Association classification (class III and IV), emergency, inotropes used intraoperatively, and prolonged cardiopulmonary bypass time (p < 0.05).

CONCLUSION

The authors identified 4 preoperative and intraoperative risk factors for prolonged ICU stay. This is helpful to identify patients with increased risk for prolonged ICU stay, implement specific strategies, and allocate medical resources.

摘要

目的

本研究旨在评估主动脉弓手术后 ICU 住院时间延长的术前和术中危险因素。

设计

回顾性研究。ICU 住院时间延长定义为 >5 天(120 小时)。

地点

心血管手术室和 ICU。

参与者

需要行主动脉弓手术并接受深低温循环停止加顺行选择性脑灌注的成年人。

干预措施

无。

测量和主要结果

在排除了 11 例行 1 期全主动脉或次全主动脉置换术的患者后,共有 298 例患者入组研究。患者的平均年龄为 44.9 +/- 10.7 岁,男性居多(74.8%)。61 例(20.5%)患者在 ICU 停留时间超过 5 天。单因素分析发现年龄、体重指数、纽约心脏协会分级、术前血肌酐、肌酐清除率、急诊、正性肌力药、体外循环时间、心肌缺血时间和术中新鲜冷冻血浆输注与 ICU 住院时间延长显著相关(p < 0.05)。延长 ICU 住院时间的独立危险因素为纽约心脏协会分级(III 级和 IV 级)、急诊、术中使用正性肌力药和体外循环时间延长(p < 0.05)。

结论

作者确定了 4 个术前和术中 ICU 住院时间延长的危险因素。这有助于识别 ICU 住院时间延长风险增加的患者,实施特定策略,并分配医疗资源。

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