Kelly Philip A, Metcalfe Karl, Evanson Jane, Sabin Ian, Plowman P Nicholas, Monson John P
Department of Endocrinology, St Bartholomew's Hospital, London E1 5AG, UK.
Horm Res. 2009;72(3):190-6. doi: 10.1159/000232496. Epub 2009 Sep 1.
Positron emission tomography (PET) with (18)F-fluorodeoxy-glucose indicates metabolically active tissue. When investigating enhancing intracranial tumours, we have suggested that PET positivity might suggest an intracranial germ cell tumour (IGCT). Here, we present a case with dicentric IGCT where PET was initially discordant between the lesions and where PET then became negative despite clearly aggressive clinical behaviour. A cautionary note is introduced with respect to the interpretation of negative (18)F-FDG PET when investigating enhancing intracranial lesions.
