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表面张力在药学中的影响。

Impact of surface tension in pharmaceutical sciences.

作者信息

Fathi Azarbayjani Anahita, Jouyban Abolghasem, Chan Sui Yung

机构信息

Department of Pharmacy, National University of Singapore.

出版信息

J Pharm Pharm Sci. 2009;12(2):218-28. doi: 10.18433/j32p40.

DOI:10.18433/j32p40
PMID:19732499
Abstract

Surface chemistry has a large influence in many industries. In the life sciences, surface area is gaining importance in the characterization of materials during their development, formulation and manufacturing. The chemical activity, adsorption, dissolution, and bioavailability of a drug may depend on the surface of the molecule. In order to meet manufacturing challenges and develop new and better performing products with improved qualities, knowledge of surface tension is of utmost importance. An attempt has been made in this paper to review the application of interfacial tension in the key domains of pharmaceutical applications.

摘要

表面化学在许多行业中都有很大影响。在生命科学领域,表面积在材料开发、制剂和制造过程中的特性表征方面正变得越来越重要。药物的化学活性、吸附、溶解和生物利用度可能取决于分子表面。为了应对制造挑战并开发出质量更好、性能更佳的新产品,了解表面张力至关重要。本文试图综述界面张力在药物应用关键领域的应用。

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