Schmidt Mads Bo, Engel Ulla Højholt, Mogensen Anne Mellon, Bülow Steffen, Petersen Lone Nørgård, Holck Susanne
Patologiafdelingen, Hvidovre Hospital, DK-2650 Hvidovre.
Ugeskr Laeger. 2009 Aug 24;171(35):2453-8.
Colorectal carcinoma is one of the most prevalent malignancies in Western countries. Lymph node status is a significant prognosticator. The chance of identifying node-positivity is positively correlated with the number of lymph nodes (LN) identified. The present paper discusses various variables that may influence the detection of LNs, including patient- as well as surgeon- and pathologist-related issues. The pathologist-related variable most probably shapes the yield the most. Introduction of guidelines focusing on the most appropriate technique may secure better and more consistent results, and the pathologist's commitment is crucial in this respect.
结直肠癌是西方国家最常见的恶性肿瘤之一。淋巴结状态是一个重要的预后指标。识别淋巴结阳性的几率与所识别的淋巴结数量呈正相关。本文讨论了可能影响淋巴结检测的各种变量，包括与患者、外科医生和病理学家相关的问题。与病理学家相关的变量很可能对检出率影响最大。引入侧重于最合适技术的指南可能会确保获得更好、更一致的结果，在这方面病理学家的投入至关重要。
