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法国16家产科单位网络中指南发布后产后出血的发生率及处理情况

Incidence and management of postpartum haemorrhage following the dissemination of guidelines in a network of 16 maternity units in France.

作者信息

Dupont C, Touzet S, Colin C, Deneux-Tharaux C, Rabilloud M, Clement H J, Lansac J, Colle M H Bouvier, Rudigoz R C

机构信息

Healthcare Practices Assessment Unit, Pole IMER des Hospices Civils de Lyon, 162, avenue Lacassagne, 69424 Lyon cedex 03, France.

出版信息

Int J Obstet Anesth. 2009 Oct;18(4):320-7. doi: 10.1016/j.ijoa.2009.02.017. Epub 2009 Sep 3.

Abstract

BACKGROUND

In France obstetric haemorrhage is the leading cause of maternal death. The aim of this study was to evaluate if the management of postpartum haemorrhage at individual maternity units followed guidelines established by the Aurore Network.

METHODS

A descriptive study was carried out in 16 maternity units of the Aurore network between October 2004 and September 2005. Cases and data were prospectively identified and collected.

RESULTS

Postpartum haemorrhage occurred in 1144 of 21 350 deliveries, an overall incidence of 5.4+/-0.3%. Of these, 316 cases were rated as severe. Diagnosis was clinical in 82.5% of severe cases and 77.5% of non-severe cases; the remainder were detected by postpartum laboratory tests. Uterotonic agents were given prophylactically to 46.7% of the 896 patients following vaginal delivery. In cases in which postpartum haemorrhage was due to uterine atony, 83.1% of women underwent examination of the uterine cavity and 96.3% received oxytocin, which proved therapeutic. Sulprostone was administered to 39.5% cases of persistent postpartum haemorrhage. A uterotonic was given prophylactically to 85.4% of the 247 patients at caesarean delivery. Oxytocin was therapeutic in 94.8% of cases of uterine atony. Sulprostone was administered in 84.4% of cases of persistent postpartum haemorrhage.

CONCLUSION

The regional guidelines issued by the Aurore network were only partially followed. More effective guideline dissemination and implementation is required to improve the prevention and management of confirmed haemorrhage.

摘要

背景

在法国,产科出血是孕产妇死亡的主要原因。本研究的目的是评估各个产科单位对产后出血的处理是否遵循了奥萝尔网络制定的指南。

方法

2004年10月至2005年9月期间,在奥萝尔网络的16个产科单位开展了一项描述性研究。对病例和数据进行前瞻性识别和收集。

结果

21350例分娩中有1144例发生产后出血,总体发生率为5.4±0.3%。其中,316例被评定为严重出血。82.5%的严重出血病例和77.5%的非严重出血病例通过临床诊断;其余病例通过产后实验室检查发现。896例阴道分娩后的患者中,46.7%预防性使用了宫缩剂。在产后出血因子宫收缩乏力所致的病例中,83.1%的女性接受了宫腔检查,96.3%接受了催产素治疗,且证明有效。39.5%持续性产后出血的病例使用了硫前列酮。247例剖宫产患者中,85.4%预防性使用了宫缩剂。94.8%子宫收缩乏力的病例使用催产素治疗有效。84.4%持续性产后出血的病例使用了硫前列酮。

结论

奥萝尔网络发布的区域指南仅得到部分遵循。需要更有效地传播和实施指南,以改善确诊出血的预防和处理。

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