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Detection of twelve nucleotides insertion in the BCR-ABL kinase domain in an imatinib-resistant but dasatinib-sensitive patient with bi-phenotypic acute leukemia.

作者信息

Hayette Sandrine, Chabane Kaddour, Tchirkov Andrei, Berger Marc G, Nicolini Franck E, Tournilhac Olivier

出版信息

Haematologica. 2009 Sep;94(9):1324-6. doi: 10.3324/haematol.2009.007864.

Abstract
摘要

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本文引用的文献

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BCR-ABL alternative splicing as a common mechanism for imatinib resistance: evidence from molecular dynamics simulations.
Mol Cancer Ther. 2008 Dec;7(12):3834-41. doi: 10.1158/1535-7163.MCT-08-0482. Epub 2008 Dec 3.
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Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib.
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