从海绵来源的真菌顶孢霉属SpF080624G1f01中分离得到的新型糖基苯二醇JBIR - 37和 - 38。

JBIR-37 and -38, novel glycosyl benzenediols, isolated from the sponge-derived fungus, Acremonium sp. SpF080624G1f01.

作者信息

Izumikawa Miho, Khan Shams Tabrez, Komaki Hisayuki, Nagai Aya, Inaba Shigeki, Takagi Motoki, Shin-Ya Kazuo

机构信息

Biomedicinal Information Research Center (BIRC), Japan Biological Informatics Consortium (JBIC), 2-42 Aomi, Koto-ku, Tokyo 135-0064, Japan.

出版信息

Biosci Biotechnol Biochem. 2009 Sep;73(9):2138-40. doi: 10.1271/bbb.90346. Epub 2009 Sep 7.

DOI:10.1271/bbb.90346

PMID:19734652

Abstract

In the course of our chemical screening program for new secondary metabolites, we isolated new compounds JBIR-37 (1) and -38 (2) from a culture broth of the marine sponge-derived fungus, Acremonium sp. SpF080624G1f01. The structures of 1 and 2 were determined to be di- and mono-O-beta-D-glucopyranosyloxy-4-(1,1-dimethyl-2-propenyl)benzene on the basis of extensive NMR and MS spectroscopic data, respectively.

摘要

在我们针对新型次生代谢产物的化学筛选项目过程中，我们从海洋海绵来源的真菌顶孢霉属SpF080624G1f01的培养液中分离出了新化合物JBIR - 37（1）和 - 38（2）。分别基于广泛的核磁共振（NMR）和质谱（MS）光谱数据，确定1和2的结构分别为二 - O-β - D - 吡喃葡萄糖氧基 - 4 -（1,1 - 二甲基 - 2 - 丙烯基）苯和单 - O-β - D - 吡喃葡萄糖氧基 - 4 -（1,1 - 二甲基 - 2 - 丙烯基）苯。