Department of Skin and STD, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Indian J Dermatol Venereol Leprol. 2009 Sep-Oct;75(5):495-8. doi: 10.4103/0378-6323.55394.
Giant congenital melanocytic nevi are rare and occur in about one out of every 2,00,000 to 5,00,000 births. There is a significant association between bathing trunk nevus and neurofibromatosis and lipomatosis. Apart from this, association of bathing trunk nevus with abnormalities like spina bifida occulta, meningocele, club foot and hypertrophy or atrophy of deeper structures of a limb, have been described. We are herewith reporting two cases of bathing trunk nevi. In our first case, an eight-year-old girl presented with a bathing trunk nevus studded with multiple, large nodules. Histopathological examination of the biopsy taken from one nodule revealed features of both neurofibroma and lipoma. To the best of our knowledge, features of both these hamartomas in one nodule of a single patient are probably not reported in the literature. In our second case, a 12-year-old girl presented with bathing trunk nevus and she had spina bifida occulta. She also had lipoma in the lesion of bathing trunk nevus. Both of our patients had satellite melanocytic nevi over the face, forearm, upper back and legs. Our second patient, in addition, had small melanocytic nevi over the medial canthus and sclerocorneal junction of the right eye. By the time this girl presented to us, the melanocytic nevus started fading in color and it had become brownish. We are reporting these cases for their peculiarities and for their rare features.
先天性巨大黑素细胞痣罕见，每 20 万至 50 万例出生中约有 1 例。泳裤痣与神经纤维瘤病和脂肪瘤之间存在显著关联。除此之外，泳裤痣还与脊柱裂、脑膜膨出、马蹄内翻足和肢体深部结构的肥大或萎缩等异常相关。我们在此报告两例泳裤痣病例。在我们的第一个病例中，一名 8 岁女孩出现了带有多个大结节的泳裤痣。从一个结节取活检进行组织病理学检查显示出神经纤维瘤和脂肪瘤的特征。据我们所知，在单个患者的单个结节中同时存在这两种错构瘤的特征可能尚未在文献中报道过。在我们的第二个病例中，一名 12 岁女孩出现了泳裤痣，同时还患有脊柱裂隐性。她的泳裤痣病变中还有脂肪瘤。我们的两位患者面部、前臂、上背部和腿部都有卫星黑素细胞痣。我们的第二位患者，右眼内眦和巩膜角膜结合处还有小的黑素细胞痣。当这个女孩来就诊时，她的黑素细胞痣开始褪色，变成了棕色。我们报告这些病例是因为它们的特殊性和罕见特征。
